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William G. Hundley, M.D.CepEsperu School of Medicine

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William G. Hundley, M.D.


Clinical Interests

Vascular Biology and Function, Cardiac Magnetic Resonance Imaging, Cardiology (clinical), Echocardiography, Computed Tomography (CT)

Contact Information

Returning Patient Appointments: -6674
Department: -6125

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Enlightenment & Training

  • B.S., College of William & Mary, 1984
  • M.D., Medical College of Va., VCU, 1988
  • Internship, Parkland Memorial Hosp, 1989
  • Residency, Parkland Memorial Hosp, 1991
  • Fellowship, Parkland Memorial Hosp, 1996

NPI Number

  • 1194700484
William G. Hundley, M.D.

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No Rating Available
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William G. Hundley, M.D.

Professor, Cardiology
Office of Women in Medicine and Science
Biomedical Engineering

Investigation Interests

Magnetic Resonance Imaging; Magnetic Resonance Imaging, Cine; Dobutamine; Ventricular Dysfunction, Left; Ventricular Function, Left
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Contact Information

Academic: -6125 | Department: -6125

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Recent Publications

Cardio-oncology: an evolving hybrid subspecialty [commentary]. Chen-Scarabelli C, Hundley WG, Scarabelli TM.. Future Cardiol. 2018;14(3):197-201.

Imaging the myocardial ischemic cascade. Stillman AE, Oudkerk M, Bluemke DA, de Boer MJ, Bremerich J, Garcia EV, Gutbertlet M, van der Harst P, Hundley WG, Jerosch-Herold M, Kuijpers D, Kwong RY, Nagel E, Lerakis S, Oshinski J, Paul JF, Slart R, Thourani V, Vliegenthart R, Wintersperger BJ.. Int J Cardiovasc Imaging. 2018;34(8):1249-1263.

Abnormalities in 3-dimensional left ventricular mechanics with anthracycline chemotherapy are associated with systolic and diastolic dysfunction. Zhang KW, Finkelman BS, Gulati G, Narayan HK, Upshaw J, Narayan V, Plappert T, Englefield V, Smith AM, Zhang C, Hundley WG, Ky B.. JACC Cardiovasc Imaging. 2018;():.

Predictive value of collagen biomarkers for heart failure with and without preserved ejection fraction: MESA (Multi-Ethnic Study of Atherosclerosis). Duprez DA, Gross MD, Kizer JR, Ix JH, Hundley WG, Jacobs DR Jr.. J Am Heart Assoc. 2018;7(5):e007885.

The role of cardiovascular magnetic resonance in the management of patients with cancer. Hundley WG.. Curr Treat Options Cardiovasc Med. 2018;20(4):30.

Added value of cardiovascular magnetic resonance in primary mitral regurgitation [editorial]. Delgado V, Hundley WG.. Circulation. 2018;137(13):1361-1363.

BOLD magnetic resonance imaging in nephrology. Hall ME, Jordan JH, Juncos LA, Hundley WG, Hall JE.. Int J Nephrol Renovasc Dis. 2018;11():103-112.

Structural and functional properties of thoracic ascending aorta in obstructive sleep apnea (the Multi-Ethnic Study of Atherosclerosis [MESA] study) [abstract]. Kwon Y, Logan J, Redline S, Duprez D, Jacobs DR, Ouyang P, Hundley WG, Lima J, Bluemke DA, Lutsey PL.. Sleep. 2018;41(Suppl 1):A176.

Left ventricular mass change after anthracycline chemotherapy. Jordan JH, Castellino SM, Melendez GC, Klepin HD, Ellis LR, Lamar Z, Vasu S, Kitzman DW, Ntim WO, Brubaker PH, Reichek N, D'Agostino RB Jr, Hundley WG.. Circ Heart Fail. 2018;11(7):e004560.

Left ventricular hypertrophy by ECG versus cardiac MRI as a predictor for heart failure. Oseni AO, Qureshi WT, Almahmoud MF, Bertoni AG, Bluemke DA, Hundley WG, Lima JA, Herrington DM, Soliman EZ.. Heart. 2017;103(1):49-54.

Reflection magnitude, a measure of arterial stiffness, predicts incident heart failure in men but not women: Multi-Ethnic Study of Atherosclerosis (MESA). Chester RC, Gornbein JA, Hundley WG, Srikanthan P, Watson KE, Horwich T.. J Card Fail. 2017;23(5):353-362.

Multimodality strategy for cardiovascular risk assessment: performance in 2 population-based cohorts. de Lemos JA, Ayers CR, Levine BD, deFilippi CR, Wang TJ, Hundley WG, Berry JD, Seliger SL, McGuire DK, Ouyang P, Drazner MH, Budoff MJ, Greenland P, Ballantyne CM, Khera A.. Circulation. 2017;135(22):2119-2132.

Hypertrabeculated left ventricular myocardium in relationship to myocardial function and fibrosis: the Multi-Ethnic Study of Atherosclerosis. Kawel-Boehm N, McClelland RL, Zemrak F, Captur G, Hundley WG, Liu CY, Moon JC, Petersen SE, Ambale-Venkatesh B, Lima JAC, Bluemke DA.. Radiology. 2017;284(3):667-675.

Racial differences in circulating levels of the soluble receptor for advanced glycation endproducts in middle-aged and older adults. Brinkley TE, Leng X, Nicklas BJ, Kritchevsky SB, Ding J, Kitzman DW, Hundley WG.. Metabolism. 2017;70():98-106.

Frequency of transition from stage A to B or C heart failure after potentially cardiotoxic chemotherapy [abstract]. Jones D, Suerken C, D'Agostino R, Melendez G, Jordan J, Hundley W.. J Am Coll Cardiol. 2017;69(11 Suppl):924.

Decreases in left ventricular mass and not left ventricular ejection fraction are associated with heart failure symptoms in cancer patients six months after potentially cardiotoxic chemotherapy [abstract]. Jordan JH, Melendez G, Suerken C, D'Agostino R, Hundley W.. J Am Coll Cardiol. 2017;69(11 Suppl):1410.

Frequency of left ventricular end-diastolic volume-mediated declines in ejection fraction in patients receiving potentially cardiotoxic cancer treatment. Melendez GC, Sukpraphrute B, D'Agostino RB Jr, Jordan JH, Klepin HD, Ellis L, Lamar Z, Vasu S, Lesser G, Burke GL, Weaver KE, Ntim WO, Hundley WG.. Am J Cardiol. 2017;119(10):1637-1642.

Magnetic resonance imaging of the heart. Hundley WG, Kramer CM, Sanz J. In: Fuster V, Harrington RA, Narula J, Espen ZJ, eds. Hurst's the heart. 14th ed. New York: McGraw-Hill Enlightenment;2017: .

Progressive 3-month increase in LV myocardial ECV after anthracycline-based chemotherapy [letter]. Melendez GC, Jordan JH, D'Agostino RB Jr, Vasu S, Hamilton CA, Hundley WG.. JACC Cardiovasc Imaging. 2017;10(6):708-709.

Effect of spironolactone on exercise tolerance and arterial function in older adults with heart failure with preserved ejection fraction. Upadhya B, Hundley WG, Brubaker PH, Morgan TM, Stewart KP, Kitzman DW.. J Am Geriatr Soc. 2017;65(11):2374-2382.

Three-dimensional volumetric assessment of diastolic function by cardiac magnetic resonance imaging: the Multi-Ethnic Study of Atherosclerosis (MESA). Nacif MS, Almeida ALC, Young AA, Cowan BR, Armstrong AC, Yang E, Sibley CT, Hundley WG, Liu S, Lima JA, Bluemke DA.. Arq Bras Cardiol. 2017;108(6):552-563.

Early myocardial strain changes during potentially cardiotoxic chemotherapy may occur as a result of reductions in left ventricular end-diastolic volume: the need to interpret left ventricular strain with volumes [research letter]. Jordan JH, Sukpraphrute B, Melendez GC, Jolly MP, D'Agostino RB Jr, Hundley WG.. Circulation. 2017;135(25):2575-2577.

Tissue evaluation using global characteristics of non-invasive imaging and systems for determining global tissue characteristics of images. Hamilton CA, Torti FM, Lane KS, Hundley WG, Morgan TM, inventors; CepEsperu University Health Sciences, assignee.. European patent office EP 2314218. 2017 Feb 1. 2017;():.

Aortic arch pulse wave velocity assessed by magnetic resonance imaging as a predictor of incident cardiovascular events: the MESA (Multi-Ethnic Study of Atherosclerosis). Ohyama Y, Ambale-Venkatesh B, Noda C, Kim JY, Tanami Y, Teixido-Tura G, Chugh AR, Redheuil A, Liu CY, Wu CO, Hundley WG, Bluemke DA, Guallar E, Lima JAC.. Hypertension. 2017;70(3):524-530.

Automated assessments of circumferential strain from cine CMR correlate with LVEF declines in cancer patients early after receipt of cardio-toxic chemotherapy. Jolly MP, Jordan JH, Melendez GC, McNeal GR, D'Agostino RB Jr, Hundley WG.. J Cardiovasc Magn Reson. 2017;19(1):59.

Cardiovascular event prediction by machine learning: the Multi-Ethnic Study of Atherosclerosis. Ambale-Venkatesh B, Yang X, Wu CO, Liu K, Hundley WG, McClelland RL, Gomes AS, Folsom AR, Shea S, Guallar E, Bluemke DA, Lima JA.. Circ Res. 2017;121(9):1092-1101.

Stroke volume and cardiac output response to maximal exercise is attenuated in anthracycline treated cancer survivors [abstract]. Larson AM, Brubaker PH, Jordan J, Hundley G [sic] [Hundley WG].. Med Sci Sports Exerc. 2017;49(5 Suppl 1):332-333.

Reproducibility of functional aortic analysis using magnetic resonance imaging: the MESA. Noda C, Ambale Venkatesh B, Ohyama Y, Liu CY, Chamera E, Redheuil A, Teixido-Tura G, Chugh AR, Wu CO, Hundley GW [sic] [Hundley WG], Bluemke DA, Lima JA.. Eur Heart J Cardiovasc Imaging. 2016;17(8):909-917.

Adverse left ventricular remodeling and age assessed with cardiac MR imaging: the Multi-Ethnic Study of Atherosclerosis. Eng J, McClelland RL, Gomes AS, Hundley WG, Cheng S, Wu CO, Carr JJ, Shea S, Bluemke DA, Lima JA.. Radiology. 2016;278(3):714-722.

Ten-year longitudinal change in aortic stiffness assessed by cardiac MRI in the second half of the human lifespan: the Multi-Ethnic Study of Atherosclerosis. Ohyama Y, Teixido-Tura G, Ambale-Venkatesh B, Noda C, Chugh AR, Liu CY, Redheuil A, Stacey RB, Dietz H, Gomes AS, Prince MR, Evangelista A, Wu CO, Hundley WG, Bluemke DA, Lima JA.. Eur Heart J Cardiovasc Imaging. 2016;17(9):1044-1053.

Reduced long axis strain is associated with heart failure and cardiovascular events in the Multi-Ethnic Study of Atherosclerosis. Gjesdal O, Yoneyama K, Mewton N, Wu C, Gomes AS, Hundley G [sic] [Hundley WG], Prince M, Shea S, Liu K, Bluemke DA, Lima JA.. J Magn Reson Imaging. 2016;44(1):178-185.

Adiposity is associated with gender-specific reductions in left ventricular myocardial perfusion during dobutamine stress. Hall ME, Brinkley TE, Chughtai H, Morgan TM, Hamilton CA, Jordan JH, Stacey RB, Soots S, Hundley WG.. PLoS One. 2016;11(1):e0146519.

Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial. Kitzman DW, Brubaker P, Morgan T, Haykowsky M, Hundley G [sic] [Hundley WG], Kraus WE, Eggebeen J, Nicklas BJ.. JAMA. 2016;315(1):36-46.

Prognosis of low normal left ventricular ejection fraction in an asymptomatic population-based adult cohort: the Multiethnic Study of Atherosclerosis. Yeboah J, Rodriguez CJ, Qureshi W, Liu S, Carr JJ, Lima JA, Hundley WG, Herrington DM.. J Card Fail. 2016;22(10):763-768.

Longitudinal automated assessments of myocardial strain from cine MR in cancer patients receiving cardiotoxic chemotherapy [abstract]. Jolly M-P, Jordan JH, Hamilton CA, Hundley G [sic] [Hundley WG].. J Cardiovasc Magn Reson. 2016;18(Suppl 1):081.

Beta-blocker use is associated with higher renal tissue oxygenation in hypertensive patients suspected of renal artery stenosis. Hall ME, Rocco MV, Morgan TM, Hamilton CA, Jordan JH, Edwards MS, Hall JE, Hundley WG.. Cardiorenal Med. 2016;6(4):261-268.

Fibroblast growth factor-23 and cardiac MRI indices of myocardial fibrosis in the Multi-ethnic Study of Atherosclerosis [abstract]. Almahmoud MF, Herrington D, Hundley W, Jordan J, Kestenbaum B, Katz R, Michos E, Liu CY, Venkatesh BA, Lima J.. J Am Coll Cardiol. 2016;67(13 Suppl):1684.

Refection magnitude, a measure of arterial stiffness, predicts incident congestive heart failure in men but not women: Multi-ethnic Study of Atherosclerosis (MESA) [abstract]. Chester R, Horwich T, Srikanthan P, Gornbein J, Hundley G [sic] [Hundley WG], Watson K.. J Am Coll Cardiol. 2016;67(13 Suppl):1314.

Association of aortic stiffness with left ventricular remodeling and reduced left ventricular function measured by magnetic resonance imaging: the Multi-Ethnic Study of Atherosclerosis. Ohyama Y, Ambale-Venkatesh B, Noda C, Chugh AR, Teixido-Tura G, Kim JY, Donekal S, Yoneyama K, Gjesdal O, Redheuil A, Liu CY, Nakamura T, Wu CO, Hundley WG, Bluemke DA, Lima JA.. Circ Cardiovasc Imaging. 2016;9(7):e004426.

Mediterranean diet score and left ventricular structure and function: the Multi-Ethnic Study of Atherosclerosis. Levitan EB, Ahmed A, Arnett DK, Polak JF, Hundley WG, Bluemke DA, Heckbert SR, Jacobs DR Jr, Nettleton JA.. Am J Clin Nutr. 2016;104(3):595-602.

Anthracycline-associated T1 mapping characteristics are elevated independent of the presence of cardiovascular comorbidities in cancer survivors. Jordan JH, Vasu S, Morgan TM, D'Agostino RB Jr, Melendez GC, Hamilton CA, Arai AE, Liu S, Liu CY, Lima JA, Bluemke DA, Burke GL, Hundley WG.. Circ Cardiovasc Imaging. 2016;9(8):e004325.

Natural history of myocardial function in an adult human population: serial longitudinal observations from MESA. Yoneyama K, Donekal S, Venkatesh BA, Wu CO, Liu CY, Souto Nacif M, Armstrong A, Gomes AS, Hundley WG, McClelland RL, Bluemke DA, Lima JA.. JACC Cardiovasc Imaging. 2016;9(10):1164-1173.

Is myocardial fibrosis a new frontier for discovery in cardiotoxicity related to the administration of anthracyclines? [editorial]. Melendez GC, Hundley WG.. Circ Cardiovasc Imaging. 2016;9(12):e005797.

Impact of aortic size and function assessed by MRI on incident hypertension and blood pressure progression: the Multi-ethnic Study of Atherosclerosis [abstract]. Ohyama Y, Ambale-Venkatesh B, Yoneyama K, Nwabuo C, Noda C, Tura GT, Redheuil A, Gomes A, Hundley G [sic] [Hundley WG], Nakamura T, Bluemke D, Lima J.. Eur Heart J. 2016;37(Suppl 1):1203.

Diagnostic tests in cardio-oncology. Biasillo G, Cardinale D, Nhola LF, Villarraga HR, Jordan JH, Hundley WG. In: Herrmann J ed. Clinical cardio-oncology. Philadelphia (PA): Elsevier;2016: 313.

Increased cardiovascular stiffness and impaired age-related functional status. Andersen MM, Kritchevsky SB, Morgan TM, Hire DG, Vasu S, Brinkley TE, Kitzman DW, Hamilton CA, Soots S, Hundley WG.. J Gerontol A Biol Sci Med Sci. 2015;70(5):545-553.

Right ventricular stress-induced perfusion defects and late gadolinium enhancement in coronary artery disease. Milks MW, Upadhya B, Hall ME, Vasu S, Hundley WG, Stacey RB.. J Comput Assist Tomogr. 2015;39(2):185-188.

Evaluation and management of left ventricular noncompaction cardiomyopathy. Stacey RB, Caine AJ Jr, Hundley WG.. Curr Heart Fail Rep. 2015;12(1):61-67.

Cigarette smoking and cardiovascular events: role of inflammation and subclinical atherosclerosis: the Multiethnic Study of Atherosclerosis. McEvoy JW, Blaha MJ, DeFilippis AP, Lima JA, Bluemke DA, Hundley WG, Min JK, Shaw LJ, Lloyd-Jones DM, Barr RG, Budoff MJ, Blumenthal RS, Nasir K.. Arterioscler Thromb Vasc Biol. 2015;35(3):700-709.

Abnormal stress-related measures of arterial stiffness in middle-aged and elderly men and women with impaired fasting glucose at risk for a first episode of symptomatic heart failure. Vasu S, Morgan TM, Kitzman DW, Bertoni A, Stacey RB, Hamilton C, Chiles C, Thohan V, Hundley WG.. J Am Heart Assoc. 2015;4(1):e000991.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Cardiology

Clinical Interests

Vascular Biology and Function, Cardiac Magnetic Resonance Imaging, Cardiology (clinical), Echocardiography, Computed Tomography (CT)
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