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Alain Bertoni, M.D.CepEsperu School of Medicine

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Alain Bertoni, M.D.


Clinical Interests

General Internal Medicine

Contact Information


Email: [email protected]

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Enlightenment & Training

  • B.A., Yale University, 1990
  • M.D., Johns Hopkins University School of Medicine, 1995
  • M.P.H., Sch Hyg & PH;Johns Hopkins U, 1999
  • Residency, Internal Medicine, Johns Hopkins Hosp, 1998
  • Fellowship, Internal Medicine, Johns Hopkins University Schoo, 2001

Board Certifications

  • American Board of Internal Medicine, Internal Medicine

NPI Number

  • 1558344259
Alain Bertoni, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

Alain Bertoni, M.D.

Director, Maya Angelou Center for Health Equity
Institute for Regenerative Medicine

Investigation Interests

Atherosclerosis; Diabetes Mellitus, Type 2; Cardiovascular Diseases; Heart Failure; Ethnic Groups
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Contact Information

Academic: -2824 | Department:

Email: [email protected]

Recent Publications

Validation of risk equations for complications of type 2 diabetes (RECODe) using individual participant data from diverse longitudinal cohorts in the U.S. Basu S, Sussman JB, Berkowitz SA, Hayward RA, Bertoni AG, Correa A, Mwasongwe S, Yudkin JS.. Diabetes Care. 2018;41(3):586-595.

Predictors and outcomes of heart failure with mid-range ejection fraction. Bhambhani V, Kizer JR, Lima JAC, van der Harst P, Bahrami H, Nayor M, de Filippi CR, Enserro D, Blaha MJ, Cushman M, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop W, Liu K, Vasan RS, Psaty BM, Lee DS, Brouwers FP, Hillege HL, Bartz TM,.. Eur J Heart Fail. 2018;20(4):651-659.

Long-term effects of an intensive lifestyle intervention on electrocardiographic criteria for left ventricular hypertrophy: the Look AHEAD trial. Brinkley TE, Anderson A, Soliman EZ, Bertoni AG, Greenway F, Knowler WC, Glasser SP, Horton ES, Espeland MA.. Am J Hypertens. 2018;31(5):541-548.

Association of cardiovascular biomarkers with incident heart failure with preserved and reduced ejection fraction. de Boer RA, Nayor M, deFilippi CR, Enserro D, Bhambhani V, Kizer JR, Blaha MJ, Brouwers FP, Cushman M, Lima JAC, Bahrami H, van der Harst P, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS,.. JAMA Cardiol. 2018;3(3):215-224.

Association between mean systolic blood pressure and cardiovascular outcomes in diabetes mellitus: ACCORD trial. Yeboah J, Byington B, Bertoni A.. J Hum Hypertens. 2018;32(2):167-169.

Comparison of measures of adiposity and cardiovascular disease risk factors among African American adults: the Jackson Heart Study. Bell RA, Chen H, Saldana S, Bertoni AG, Effoe VS, Hairston KG, Kalyani RR, Norwood AF.. J Racial Ethn Health Disparities. 2018;():.

Metabolic syndrome is associated with impaired diastolic function independently of MRI-derived myocardial extracellular volume: the MESA study. Ladeiras-Lopes R, Moreira HT, Bettencourt N, Fontes-Carvalho R, Sampaio F, Ambale-Venkatesh B, Wu C, Liu K, Bertoni AG, Ouyang P, Bluemke DA, Lima JA.. Diabetes. 2018;67(5):1007-1012.

Invited commentary: sex and race differences in diabetes and cardiovascular disease-achieving the promise of sex and race subgroup analyses in epidemiologic research. Moise N, Bertoni AG.. Am J Epidemiol. 2018;187(3):411-414.

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H, Taliun D, Rayner NW, Guo X, Lu Y, Li M, Jensen RA, Hu Y, Huo S, Lohman KK, Zhang W, Cook JP, Prins BP, Flannick J, Grarup N, Trubetskoy VV, Kravic J, Kim YJ,.. Nat Genet. 2018;50(4):559-571.

Endogenous sex hormones and incident cardiovascular disease in post-menopausal women. Zhao D, Guallar E, Ouyang P, Subramanya V, Vaidya D, Ndumele CE, Lima JA, Allison MA, Shah SJ, Bertoni AG, Budoff MJ, Post WS, Michos ED.. J Am Coll Cardiol. 2018;71(22):2555-2566.

New statin use and left ventricular structure: estimating long-term associations in the Multi-Ethnic Study of Atherosclerosis (MESA). Strand LN, Young RL, Bertoni AG, Bluemke DA, Burke GL, Lima JA, Sotoodehnia N, Psaty BM, McClelland RL, Heckbert SR, Delaney JA.. Pharmacoepidemiol Drug Saf. 2018;27(6):570-580.

Left ventricular hypertrophy by ECG versus cardiac MRI as a predictor for heart failure. Oseni AO, Qureshi WT, Almahmoud MF, Bertoni AG, Bluemke DA, Hundley WG, Lima JA, Herrington DM, Soliman EZ.. Heart. 2017;103(1):49-54.

Percent emphysema and daily motor activity levels in the general population: Multi-Ethnic Study of Atherosclerosis. Lo Cascio CM, Quante M, Hoffman EA, Bertoni AG, Aaron CP, Schwartz JE, Avdalovic MV, Fan VS, Lovasi GS, Kawut SM, Austin JH, Redline S, Barr RG.. Chest. 2017;151(5):1039-1050.

Sex differences in the association between insulin resistance and incident coronary heart disease and stroke among blacks without diabetes mellitus: the Jackson Heart Study. Effoe VS, Wagenknecht LE, Echouffo Tcheugui JB, Chen H, Joseph JJ, Kalyani RR, Bell RA, Wu WH, Casanova R, Bertoni AG.. J Am Heart Assoc. 2017;6(2):e004229.

Geographic information systems to assess external validity in randomized trials. Savoca MR, Ludwig DA, Jones ST, Jason Clodfelter K, Sloop JB, Bollhalter LY, Bertoni AG.. Am J Prev Med. 2017;53(2):252-259.

High-sensitive cardiac troponin T as an early biochemical signature for clinical and subclinical heart failure: MESA (Multi-Ethnic Study of Atherosclerosis). Seliger SL, Hong SN, Christenson RH, Kronmal R, Daniels LB, Lima JA, de Lemos JA, Bertoni AG, deFilippi CR.. Circulation. 2017;135(16):1494-1505.

Diabetes status modifies the association between carotid intima-media thickness and incident heart failure: the Atherosclerosis Risk in Communities Study. Effoe VS, McClendon EE, Rodriguez CJ, Wagenknecht LE, Evans GW, Chang PP, Bertoni AG.. Diabetes Res Clin Pract. 2017;128():58-66.

Diabetes, depressive symptoms, and functional disability in African Americans: the Jackson Heart Study. Kalyani RR, Ji N, Carnethon M, Bertoni AG, Selvin E, Gregg EW, Sims M, Golden SH.. J Diabetes Complications. 2017;31(8):1259-1265.

Changes in metabolic risk factors over 10 years and their associations with late-life cognitive performance: the Multi-Ethnic Study of Atherosclerosis. Hughes TM, Craft S, Baker LD, Espeland MA, Rapp SR, Sink KM, Bertoni AG, Burke GL, Gottesman RF, Michos ED, Luchsinger JA, Fitzpatrick AL, Hayden KM.. Alzheimers Dement (Amst). 2017;8():18-25.

Genome-wide physical activity interactions in adiposity - a meta-analysis of 200,452 adults. Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi Q, Ngwa JS, Renstrom F, Quaye L, Eicher JD, Hayes JE, Cornelis M,.. PLoS Genet. 2017;13(4):e1006528.

Electrocardiographic predictors of heart failure with reduced versus preserved ejection fraction: the Multi-Ethnic Study of Atherosclerosis. O'Neal WT, Mazur M, Bertoni AG, Bluemke DA, Al-Mallah MH, Lima JAC, Kitzman D, Soliman EZ.. J Am Heart Assoc. 2017;6(6):e006023.

Pulmonary vascular volume, impaired left ventricular filling and dyspnea: the MESA Lung Study. Aaron CP, Hoffman EA, Lima JAC, Kawut SM, Bertoni AG, Vogel-Claussen J, Habibi M, Hueper K, Jacobs DR Jr, Kalhan R, Michos ED, Post WS, Prince MR, Smith BM, Ambale-Venkatesh B, Liu CY, Zemrak F, Watson KE, Budoff M, Bluemke DA, Barr RG.. PLoS One. 2017;12(4):e0176180.

Individual- and area-level SES in diabetes risk prediction: the Multi-Ethnic Study of Atherosclerosis. Christine PJ, Young R, Adar SD, Bertoni AG, Heisler M, Carnethon MR, Hayward RA, Diez Roux AV.. Am J Prev Med. 2017;53(2):201-209.

The American Heart Association ideal cardiovascular health and incident type 2 diabetes mellitus among blacks: the Jackson Heart Study. Effoe VS, Carnethon MR, Echouffo-Tcheugui JB, Chen H, Joseph JJ, Norwood AF, Bertoni AG.. J Am Heart Assoc. 2017;6(6):e005008.

Abdominal aortic calcification among individuals with and without diabetes: the Jackson Heart Study. Echouffo-Tcheugui JB, Allison M, Kalyani RR, Sims M, Bertoni AG, Golden SH.. Diabetes Care. 2017;40(8):e106-e107.

Physical activity, body mass index and waist circumference change, and normal-range glycated hemoglobin on incident diabetes: Jackson Heart Study. Edwards MK, Addoh O, Sng E, Ikuta T, Carithers T, Bertoni AG, Loprinzi PD.. Postgrad Med. 2017;129(8):842-848.

Differences in natriuretic peptide levels by race/ethnicity (from the Multi-Ethnic Study of Atherosclerosis). Gupta DK, Daniels LB, Cheng S, deFilippi CR, Criqui MH, Maisel AS, Lima JA, Bahrami H, Greenland P, Cushman M, Tracy R, Siscovick D, Bertoni AG, Cannone V, Burnett JC, Carr JJ, Wang TJ.. Am J Cardiol. 2017;120(6):1008-1015.

Aldosterone, renin, cardiovascular events, and all-cause mortality among African Americans: the Jackson Heart Study. Joseph JJ, Echouffo-Tcheugui JB, Kalyani RR, Yeh HC, Bertoni AG, Effoe VS, Casanova R, Sims M, Wu WC, Wand GS, Correa A, Golden SH.. JACC Heart Fail. 2017;5(9):642-651.

Adult height, prevalent coronary artery calcium score, and incident cardiovascular disease outcomes in a multi-ethnic cohort. Yeboah J, Blaha MJ, Michos ED, Qureshi W, Miedema M, Flueckiger P, Rodriguez CJ, Szklo M, Bertoni AG.. Am J Epidemiol. 2017;186(8):935-943.

Accuracy of self-reported heart failure. The Atherosclerosis Risk in Communities (ARIC) study. Camplain R, Kucharska-Newton A, Loehr L, Keyserling TC, Layton JB, Wruck L, Folsom AR, Bertoni AG, Heiss G.. J Card Fail. 2017;23(11):802-808.

Impact of common genetic determinants of hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: a transethnic genome-wide meta-analysis. Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, Porneala BC, Sharp SJ, Jia Y, Kabagambe EK, Chang LC, Chen WM, Elks CE, Evans DS, Fan Q,.. PLoS One. 2017;14(9):e1002383.

Patient portal utilization among ethnically diverse low income older adults: observational study. Arcury TA, Quandt SA, Sandberg JC, Miller DP Jr, Latulipe C, Leng X, Talton JW, Melius KP, Smith A, Bertoni AG.. JMIR Med Inform. 2017;5(4):e47.

Coronary artery calcium score for long-term risk classification in individuals with type 2 diabetes and metabolic syndrome from the Multi-Ethnic Study of Atherosclerosis. Malik S, Zhao Y, Budoff M, Nasir K, Blumenthal RS, Bertoni AG, Wong ND.. JAMA Cardiol. 2017;2(12):1332-1340.

Cardiovascular health in African Americans a scientific statement from the American Heart Association. Carnethon MR, Pu J, Howard G, Albert MA, Anderson CAM, Bertoni AG, Mujahid MS, Palaniappan L, Taylor HA Jr, Willis M, Yancy CW.. Circulation. 2017;136(21):E393-E423.

From neighborhood to genome: three decades of nutrition-related research from the Atherosclerosis Risk in Communities Study [commentary]. Savoca MR, Steffen LM, Bertoni AG, Wagenknecht LE.. J Acad Nutr Diet. 2017;117(12):.

The use of propensity score matching to estimate the association between new statin use and left ventricular structure: in the Multi-Ethnic Study of Atherosclerosis (MESA) [abstract]. Strand LN, Bertoni AG, Bluemke DA, Lima JA, Psaty BM, Heckbert SR, Delaney JAC, McClelland RL.. Pharmacoepidemiol Drug Saf. 2017;26(Suppl 2):419.

Association of asymptomatic bradycardia with incident cardiovascular disease and mortality: the Multi-Ethnic Study of Atherosclerosis (MESA). Dharod A, Soliman EZ, Dawood F, Chen H, Shea S, Nazarian S, Bertoni AG.. JAMA Intern Med. 2016;176(2):219-227.

Aldosterone, renin and diabetes mellitus in African Americans: the Jackson Heart Study. Joseph JJ, Echouffo-Tcheugui JB, Kalyani RR, Yeh HC, Bertoni AG, Effoe VS, Casanova R, Sims M, Correa A, Wu WC, Wand GS, Golden SH.. J Clin Endocrinol Metab. 2016;101(4):1770-1778.

The obesity and heart failure epidemics among African Americans: insights from the Jackson Heart Study. Krishnamoorthy A, Greiner MA, Bertoni AG, Eapen ZJ, O'Brien EC, Curtis LH, Hernandez AF, Mentz RJ.. J Card Fail. 2016;22(8):589-597.

Cardiovascular risk factor targets and cardiovascular disease event risk in diabetes: a pooling project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study. Wong ND, Zhao Y, Patel R, Patao C, Malik S, Bertoni AG, Correa A, Folsom AR, Kachroo S, Mukherjee J, Taylor H, Selvin E.. Diabetes Care. 2016;39(5):668-676.

Ambulatory blood pressure monitoring phenotypes among individuals with and without diabetes taking antihypertensive medication: the Jackson Heart Study. Bromfield SG, Shimbo D, Bertoni AG, Sims M, Carson AP, Muntner P.. J Hum Hypertens. 2016;30(12):731-736.

Nine-year effects of 3.7 years of intensive glycemic control on cardiovascular outcomes. Gerstein HC, Beavers DP, Bertoni AG, Bigger JT, Buse JB, Craven TE, Cushman WC, Fonseca V, Geller NL, Giddings SJ, Grimm RH, Genuth S, Hramiak I, Ismail-Beigi F, Jimenez CRL, Kirby R, Probsfield J, Riddle MC, Seaquist ER, Friedewald WT.. Diabetes Care. 2016;39(5):701-708.

Predictors of longitudinal change in insulin resistance and beta-cell function in African Americans without diabetes: the Jackson Heart Study [abstract]. Effoe VS, Chen H, Echouffo-Tcheugui JB, Bell RA, Correa A, Joseph JJ, Hairston KG, Kalyani RR, Bertoni AG.. In: Abstracts of the 2016 Annual Meeting of the American Diabetes Association; 2016 June 10-14; New Orleans (LA). 2016;():1563-P.

The association of ideal cardiovascular health with incident type 2 diabetes mellitus: the Multi-Ethnic Study of Atherosclerosis. Joseph JJ, Echouffo-Tcheugui JB, Carnethon MR, Bertoni AG, Shay CM, Ahmed HM, Blumenthal RS, Cushman M, Golden SH.. Diabetologia. 2016;59(9):1893-1903.

Immigrant status and cardiovascular risk over time: results from the Multi-Ethnic Study of Atherosclerosis. Le-Scherban F, Albrecht SS, Bertoni A, Kandula N, Mehta N, Diez Roux AV.. Ann Epidemiol. 2016;26(6):429-435.e1.

Physical activity, sedentary behaviors and the incidence of type 2 diabetes mellitus: the Multi-Ethnic Study of Atherosclerosis (MESA). Joseph JJ, Echouffo-Tcheugui JB, Golden SH, Chen H, Jenny NS, Carnethon MR, Jacobs D Jr, Burke GL, Vaidya D, Ouyang P, Bertoni AG.. BMJ Open Diabetes Res Care. 2016;4(1):e000185.

Neighborhood environments and incident hypertension in the Multi-Ethnic Study of Atherosclerosis. Kaiser P, Diez Roux AV, Mujahid M, Carnethon M, Bertoni A, Adar SD, Shea S, McClelland R, Lisabeth L.. Am J Epidemiol. 2016;183(11):988-997.

Left ventricular area on non-contrast cardiac computed tomography as a predictor of incident heart failure - The Multi-Ethnic Study of Atherosclerosis. Bittencourt MS, Blankstein R, Mao S, Rivera JJ, Bertoni AG, Shaw LJ, Blumenthal RS, Budoff MJ, Nasir K.. J Cardiovasc Comput Tomogr. 2016;10(6):500-506.

Body fat distribution, menopausal hormone therapy and incident type 2 diabetes in postmenopausal women of the MESA study. Ebong IA, Watson KE, Hairston KG, Carnethon MR, Ouyang P, Szklo M, Bertoni AG.. Maturitas. 2016;91():147-152.

Development and validation of risk prediction models for cardiovascular events in black adults: the Jackson Heart Study cohort. Fox ER, Samdarshi TE, Musani SK, Pencina MJ, Sung JH, Bertoni AG, Xanthakis V, Balfour PC Jr, Shreenivas SS, Covington C, Liebson PR, Sarpong DF, Butler KR, Mosley TH, Rosamond WD, Folsom AR, Herrington DM, Vasan RS, Taylor HA.. JAMA Cardiol. 2016;1(1):15-25.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.


Clinical Interests

General Internal Medicine
Alain Bertoni, M.D.

Alain Bertoni, M.D.

Director, Maya Angelou Center for Health Equity
Institute for Regenerative Medicine

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