What we are studying
The purpose of the study is to compare the effects, good and or bad, of one drug against another drug. This large multi-country study assesses an experimental (investigational) anti-cancer drug called plinabulin (BPI-2358) and a marketed anti-cancer drug call docetaxel (Taxotere®). In this study, Plinabulin combined with Docetaxel will be compared to Docetaxel with a placebo.
This is a Phase 3 study which means that there is a fair amount information already available on the safety and efficacy of this compound and the study is being done in order to confirm the treatment effect learned from smaller scale studies done previously. The specific purposes of this study are to compare survival, tumor shrinkage, tumor regrowth and side effects in patients with lung cancer treated with docetaxel to patients treated with docetaxel and plinabulin.