Study of tissue from bladder biopsy to determine the best treatment

What we are studying

The primary focus of this study is to see if looking at tumor biomarkers using a program called “coexpression extrapolation or COXEN” may predict study participants response to chemotherapy before surgery.

Who is Eligible

  • Genders:
    • Men
    • Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18 - 80

Eligibility Criteria

  • Bladder cancer that has spread to the muscle

What is involved

  • Study participants will be randomized to receive chemotherapy based on what tests that are done to their tumor tissue show. Subjects will receive either gemcitabine
  • Cisplatin and possibly filgrastim/pegfilgrastim or methotrexate
  • Vinblastine
  • Doxorubicin
  • Cisplatin and filgrastim/pegfilgrastim.



Contact Information

Study Coordinator
Patricia Smith
[email protected]

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.