What we are studying
Atrial fibrillation (AF) (an abnormal, rapid heart rhythm coming from the upper chambers of the heart [atria]) is the most common type of heart rhythm disorder or arrhythmia (abnormal heart rhythm). Instead of the heart beating in a steady pattern, in AF the upper chambers of the heart (atria) quiver rapidly in an unsteady manner. Atrial fibrillation may be treated with drug therapy. In some Institutions, atrial fibrillation is also treated with catheters inserted into blood vessels that can be placed inside the heart to eliminate the hot spots or triggers that start atrial fibrillation or stop those conditions that keep it going (catheter ablation). It is not known whether drug therapy or catheter ablation is better.
This study is being done to compare drug therapy and catheter ablation in patients with atrial fibrillation. This study will help decide which treatment approach is best or when one or the other therapy is preferred. The CABANA study will also compare the cost of care for the two treatment approaches and determine the effect these therapies have on quality of life.